Study With Me : Introduction to Blood Transfusion 37

Question 195:

What are acquired defects in the context of coagulation defects?

The answer: Acquired defects are abnormalities that develop in an otherwise normal individual and include conditions like quantitative thrombocytopenia, drug-induced qualitative platelet deficiency, deficiencies of FII, FVII, FIX, and FX, and disseminated intravascular coagulation (DIC).

Question 196:

What is quantitative thrombocytopenia, and how can it be acquired?

The answer: Quantitative thrombocytopenia refers to a low number of platelets in the body. It can be acquired as a result of massive transfusions of stored blood, which lack functional platelets.

Question 197:

How can drug-induced qualitative platelet deficiency occur?

The answer: Drug-induced qualitative platelet deficiency occurs due to the influence of circulating drugs, leading to poor-quality platelets that do not function normally.