Question 174:
What is the origin of platelets (thrombocytes)?
Answer: Platelets originate from the cytoplasm of bone marrow cells called megakaryocytes.
Question 175:
What is the role of platelets in blood coagulation?
Answer: Platelets participate in blood coagulation by forming a plug to seal damaged blood vessels, crucial for haemostasis.
Question 176:
What are reticulocytes, and how are they identified in the bloodstream?
Answer: Reticulocytes are immature red cells with remnants of the cell nucleus. They are identified in the bloodstream by their elevated number, particularly in anaemic individuals.
Question 177:
What are the red cell abnormalities associated with chronic anaemia?
Answer: Red cell abnormalities leading to chronic anaemia include thalassaemia and sickle cell anaemia.
Question 178:
What is thalassaemia, and what causes it?
Answer: Thalassaemia is an inherited disorder, primarily in Asia and the Eastern Mediterranean, caused by a quantitative abnormality in the alpha or beta-globin chain in the haemoglobin molecule, leading to shortened red cell lifespan.