Guide to the preparation, use and quality assurance of blood components 22

Discover the EDQM’s 22nd Edition Blood Guide: A Vital Resource for Blood Transfusion Professionals.
The European Directorate for the Quality of Medicines & HealthCare (EDQM) has released the 22nd edition of the Guide to the Preparation, Use and Quality Assurance of Blood Components, commonly known as the Blood Guide. This comprehensive guide serves as an essential technical reference for healthcare professionals, regulators, policymakers, and all those involved in blood donation and transfusion.
🩸 What Is the EDQM Blood Guide?
The EDQM Blood Guide is a compendium of harmonised European technical standards that provide safety, efficacy, and quality requirements for the preparation, use, and quality control of blood components. It is widely used in over 90 countries and is considered a gold standard in blood transfusion.
📘 What’s New in the 22nd Edition?
The latest edition includes:
A complete review of all chapters.
An in-depth revision of the Haemovigilance chapter.
Addition of two new chapters: Blood components for topical use or injection and Blood supply contingency and emergency planning.
Significant changes in donor selection criteria, including considerations for Creutzfeldt–Jakob disease, malaria, blood pressure and pulse, plasmapheresis, iron stores, donor age, and insulin.
Standardisation of terminology.
👥 Who Should Use This Guide?
The Blood Guide is intended for:
Healthcare professionals involved in blood donation and transfusion.
Regulators and policymakers overseeing blood transfusion services.
Blood establishments and hospital blood banks.
🌐 Why Is It Valuable?
The guide supports professionals in applying common, harmonised standards in blood transfusion to protect donors and benefit recipients worldwide. It provides state-of-the-art recommendations and guidelines developed by experts nominated by the European Committee on Blood Transfusion (CD-P-TS).
📥 Download the 22nd Edition
The 22nd edition of the Blood Guide is available for free download:
For more information, visit the EDQM Blood Guide page.

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