Study With Me : Introduction to Blood Transfusion 35

Question 187: What is the coagulation cascade in haemostasis?

The answer: The coagulation cascade is the process where clotting factors, activated in a cascade, form a mesh of insoluble fibrin, resulting in a platelet plug and clot formation.

Question 188: What is the role of plasmin in haemostasis?

The answer: Plasmin is the enzyme responsible for the gradual absorption of the clot by the body, facilitating a return to normal in haemostasis.

Question 189: What are clotting factors in the context of blood coagulation?

The answer: Clotting factors are proteins that initiate and regulate the blood coagulation process, acting in a cascade to form a fibrin clot and stop bleeding.

Question 190: How do clotting factors circulate in the bloodstream?

The answer: Clotting factors circulate as inactive precursors in the bloodstream, and when activated, they initiate the clotting cascade leading to the formation of a fibrin clot.